Table 3.

Association of slow gait speed with depressive symptoms trajectory groups with all study participants with CES-D scores at baseline. Unadjusted and Adjusted^* Odds Ratio (OR) and 95% Confidence Interval (CI). Gait speed was categorized as >1.2 m/s, healthy gait speed; < 1.2 m/s, slow gait speed.

		Unadjusted OR [95% CI]	Adjusted OR [95% CI]
Trajectory Group	Difficulty walking at a community speed[%]	Slow gait speed vs Healthy gait speed	Slow gait speed vs Healthy gait speed
No depressive symptoms (n=916)	16.3	1.0 Ref	1.0 Ref
Mild depressive symptoms (n=1403)	23.4	1.5 [1.3, 1.9]	1.4 [1.1, 1.7]
Mild/Moderate depressive symptoms (n=1138)	29.3	2.1 [1.7, 2.6]	1.6 [1.3, 2.1]
Worsening moderate depressive symptoms (n=654)	37.2	3.0 [2.4, 3.9]	2.1 [1.6, 2.7]
Worsening severe depressive symptoms (n=225)	45.8	4.3 [3.2, 6.0]	3.1 [2.2, 4.4]

^*Adjusted for age, sex, BMI, comorbidity, race, education, radiographic knee OA, knee pain intensity, and lower-body pain.