Table 2.

Copper catalyzed azide-alkyne cycloaddition.

Alkyne	Azide	Cycloadducta	Yield %
1a	2a	3a	95
1b	2a	3b	94
1b	2b	3c	75
1c	2a	3d	90
1e	2a	3e	76
1b	2c	3f	78
1e	2c	3g	92
1d	2c	3h	91
1b	2d	3i	85
1a	2d	3j	87
1f	2a	3k	95
1e	2d	3l	77
1f	2d	3m	67

^aMethod: CuI (5 mol %), water, 70 °C, 2 h.