Table 1.
Examples of polymers used for nanoparticle formulation for gene delivery in lung cancer therapy
| Polymer(s) | Gene therapy tool(s) | Lung cancer type/model | References |
|---|---|---|---|
| PLGA | siRNA | A549 | [39] |
| PLGA | Plasmid DNA | A549 | [44] |
| PLGA/Chitosan | Oligonucleotides/siRNA | A549 | [41] |
| PEI/AH-PEG | siRNA | A549 | [50] |
| PEG-PEI | Plasmid DNA | A549 | [55] |
| PEI-PSOT | siRNA | A549 | [56] |
| PLL-alkyl-PEI | shRNA | – | [51] |
| Chitosan | 2′-O-methyl-RNA | A549 | [63] |
| Chitosan | siRNA | A549 | [66] |
| Chitosan | siRNA | H1299 | [64] |
| Chitosan-graft-PEI | siRNA | A549 | [65] |
| Poly (propyleneimine) (PPI) dendrimers | siRNA | A549 | [75] |
| Poly (amidoamine) (PAMAM) | Plasmid DNA | A549 | [76] |
| Poly (amidoamine) (PAMAM) | siRNA | A549 | [77] |
| Polymer micelles | siRNA | A549 | [83, 84] |