Fig. 1.
Linear regression of decorrelation signal (DBM) due to bulk motion as a function of the natural logarithmic tissue reflectance (R). Panel A shows a 6mm × 8mm (horizontal x vertical) OCT angiography scan (400B-frames × 850pixels) from which frames 134, 208, and 336 were selected as examples for moderate, low, and high bulk motion. Panel B shows the cross-sectional B-scans of frames 134 (subtle bulk motion), 208 (moderate bulk motion) and 336 (high bulk motion near microsaccade). SSADA decorrelation signal in red color is overlaid on top of the reflectance OCT signal. Panel C shows the corresponding linear fit of the binned R vs. DBM for the central segment indicated by a red arrow in B. In panel D it is observed that the RMS deviation of un-binned D of non-flow voxels from the fitting curve found at each segment exhibit a linear dependence on the corresponding segment’s slope, shown for all segments forming a volumetric scan.