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. 2017 May 23;8(6):3053–3066. doi: 10.1364/BOE.8.003053

Fig. 2.

Fig. 2

Removal of bulk motion from voxels within each B-frame segment. (A) Decorrelation due to bulk motion (DBM) is modeled as a function of logarithmic reflectance R based linear regression coefficients mk and nk from the regression analysis of the kth frame segment. Voxels with decorrelation value below threshold DTH set at the 97.5 percentile of bulk motion (assuming normal distribution) are classified as non-flow voxels (D set to zero). The bulk motion-induced decorrelation in blood DBM,blood is calculated using the reflectance of bloodRbloodobtained from the median reflectance of flow voxels (voxel with D above DTH). Bulk motion velocity vBM is obtained from DBM,blood using Eq. (2). (B) The bulk motion velocity is subtracted from a voxel with uncorrected decorrelation value D0 and corresponding velocity v0 that is high relative to the saturation velocity according to the nonlinear curve relating flow signal D to velocity. Therefore subtracting vBM from v0 to obtained corrected velocity v1and corrected flow signal D1 has little effect. (C) The bulk motion velocity is subtracted from a voxel with uncorrected decorrelation value D0 and corresponding velocity v0 that is lower than the saturation velocity. Here subtracting vBM from v0 to obtained corrected velocity v1and corrected flow signal D1 has a larger effect than the previous example.