TABLE 1.

Summary of patient characteristics and clinical interventions in case reports published in English of localized S. apiospermum soft tissue infections, listed in chronologic order of publication

Case no.	Age (yr)	Sexa	Predisposing conditionb	Infection location	Antifungal(s) usedc	Surgical treatment	Lymphangitic spread	Treatment success	Source of reference
1	24	M	Surgical wound	Scalp	MIC	N	N	+	26
2	50	F	None identified	Leg	MIC, KTC	Y	N	+	44
3	58	M	Cardiac transplant	Knee	MIC	Y	N	+	38
4	51	M	Traumatic injury	Foot	AMB, MIC, ITC	Y	N	+	40
5	45	M	Renal transplant	Knee	ITC	Y	N	+	28
6	63	M	AML and chemotherapy	Leg	ITC	N	Y	+	46
7	71	M	AML and chemotherapy	Foot	FLC, AMB, ITC	N	N	+	9
8	63	M	AML and chemotherapy	Foot	ITC	Y	N	+	42
9	59	M	Corticosteroids (nephrotic syndrome)	Arm	ITC	N	Y	+	17
10	67	M	Corticosteroids (asthma)	Hand	FLC	N	N	+	23
11	42	M	Corticosteroids (Addison's disease)	Face	ITC	N	N	+	27
12	66	F	None identified	Arm	ITC	N	N	+	43
13	69	M	Corticosteroids (polymyositis)	Hand	Topical antifungal	N	N	−	31
14	81	M	Corticosteroids (pulmonary fibrosis)	Arm	ITC	N	Y	−	4
15	65	M	Cardiac transplant	Arm	ITC, MIC	Y	N	+	13
16	65	F	Corticosteroids (osteoarthritis)	Arm	ITC	Y	Y	+	21
17	48	M	Traumatic injury	Hand	ITC	Y	N	+	21
18	64	M	Corticosteroids (sarcoidosis)	Arm	KTC, ITC	N	N	+	25
19	69	F	Corticosteroids (rheumatoid arthritis)	Arm	ITC	Y	Y	+	5
20	60	M	Renal transplant	Foot	ITC	Y	N	−	30
21	58	M	Renal transplant	Leg	ITC, VRC	N	Y	+	32
22	49	M	Bone marrow transplant	Foot	AMB, MIC, ITC	N	N	−	35
23	59	M	Renal transplant	Hand	ITC, VRC	N	N	+	3
24	84	M	Corticosteroids (COPD)	Arm	VRC	N	N	+	3
25	63	F	Corticosteroids, cyclosporine (rheumatoid arthritis)	Arm	ITC	N	Y	+	7
26	27	F	None identified	Foot	TRB (plus topical CLT)	N	N	+	20
27	58	M	Renal transplant	Foot	FLC, ITC, MIC	Y	N	+	41
28	58	F	Corticosteroids (Behçet's disease)	Arm	VRC	Y	Y	+	This report

^aM, male; F, female.

^bAML, acute myelogenous leukemia; COPD, chronic obstructive pulmonary disease.

^cMIC, miconazole; KTC, ketoconazole; AMB, amphotericin B; ITC, itraconazole; FLC, fluconazole; VRC, voriconazole; TRB, terbinafine; CLT, clotrimazole.