Fig. 9.

(a) Images of silicone sections used to calculate absorption and reduced scattering coefficients at multiple wavelengths. Materials A, B, and C were white silicone sheets of different thicknesses and durometers. Material D was gray silicone; however, it was too opaque to obtain optical parameter data. (b) Reduced scattering coefficients as a function of wavelength for each material tested. (c) Absorption coefficients as a function of wavelength for each material tested. (d) Average fluorescence depth estimates of the simulated silicone vessel under the silicone sheets for each material using the optical parameter approach. Materials B and C were each stacked to show multiple depth estimates for the same material. (e) Average depth estimate deviation from measured for each material. (f) Average fluorescence depth estimates in vivo using the optical parameter approach. (g) Average depth estimate deviation from measured for each tumor.