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. 2017 Jun 19;10:1179064417713197. doi: 10.1177/1179064417713197

Figure 3.

Figure 3

(A) Histopathological analysis (hematoxylin-eosin stained) of tumors derived from MDA-MB-231 cells in NSG mice shows large tumors distributed through the lungs in animals treated with vehicle alone but only small and infrequent tumors in the lungs of animals treated with the WAHM1 stapled peptide. (B) Analysis of Ki67 staining in primary tumors in the fat pads shows no significant difference in mice treated with either the vehicle or the WHAM1 peptide. (C) Analysis of tumor vasculature using CD31 antibodies shows a significant reduction in the number of microvessels in the primary tumors treated with the WHAM1 peptide compared with animals treated with the vehicle alone. *P < .05. Images in B and C were counterstained with hematoxylin.