Table 3. . Docetaxel loading (1.5 mg/15 mg polymer, n = 1).
| Polymer | Particle size (volume%, width) (nm) | Drug/polymer (w/w) (%) | Loading efficiency (%) |
|---|---|---|---|
| PEG5K-CA8 |
13.3 (100, 8.01) |
10 |
69 |
| 1 |
10.5 (100, 7.91) |
10 |
74 |
| 2 |
12.9 (100, 7.88) |
10 |
100 |
| 3 |
19.6 (95, 16.67)/295.4 (5, 312) |
10 |
0 |
| 4 |
9.35 (100, 7.78) |
10 |
Precipitated |
| 5 |
11.8 (100, 10.3) |
10 |
100 |
| 6 |
10.8 (100, 8.3) |
10 |
77 |
| 7 |
13.6 (95.1, 12.53)/122.8 (4.9, 206.5) |
10 |
90 |
| 8 |
13 (100, 10.33) |
10 |
2 |
| 9 |
12.4 (93.9, 9.65)/338 (6.1, 226.5) |
10 |
61 |
| 10 |
12.3 (100, 7.67) |
10 |
100 |
| 11 |
11 (95.9, 9.42)/1087 (4.1, 2586) |
10 |
21 |
| 12 |
16.1 (100, 9.07) |
10 |
1 |
| 14 |
19.7 (100, 8.88) |
10 |
85 |
| 18 | 6.5 (19.8, 2)/11.3 (24.2, 5.4)/33.6 (50.5, 27.8)/173.6 (5.5, 109.9) | 10 | 18 |
PEG: Polyethylene glycol; CA: Cholic acid.