TABLE 7.
Estimated specificities of C. trachomatis diagnostic tests performed on urine stratified by subjects' characteristics
| Characteristics of subjects tested | % Specifity (95% CI)a for urine test type:
|
|
|---|---|---|
| LCRb | PCRc | |
| All subjects | 99.2 (98.0, 100) | 99.4 (99.0, 99.8) |
| Age (yr) | ||
| <20 | 99.2 (97.8, 100) | 98.7 (97.4, 99.9) |
| ≥20 | 99.1 (98.1, 100) | 99.5 (99.2, 99.8) |
| Mucopurulent endocervical discharge | ||
| Present | 98.5 (97.3, 99.6) | 97.4 (92.5, 100) |
| Absent | 99.2 (97.9, 100) | 99.5 (99.2, 99.8) |
| Dysuria | ||
| Present | 98.8 (97.2, 100) | 100.0 (98.2, 100) |
| Absent | 99.2 (98.0, 100) | 99.4 (99.0, 99.7) |
| Hematuriad | ||
| Yes | 98.9 (97.6, 100) | 99.3 (98.6, 100) |
| No | 99.2 (98.3, 100) | 99.6 (99.1, 100) |
| Urine leukocyte esterase positive | ||
| Yes | 99.0 (97.8, 100) | 99.2 (98.5, 99.9) |
| No | 99.0 (97.5, 100) | 99.5 (99.2, 99.9) |
a
Adjusted for variation in test performance across centers. Performance defined as described in text using two reference standards (culture-PCR and culture-LCR); estimates are reported separately for each.
b
Reference standard was culture-PCR (positive results by culture or PCR).
c
Reference standard was culture-LCR (positive results by culture or LCR).
d
Defined as presence of blood on urine dipstick test.