TABLE 3.
Isolates clustered by the combination of spoligotyping and MIRU typing
| Spoligotype | MIRU pattern | IS6110 fingerprint result
|
Patient birthplacec | Length of residency prior to diagnosis (yr)d | Transmission links identified? | ||
|---|---|---|---|---|---|---|---|
| No. of exact-match isolates (no. of bands)a | No. of + 1 band isolates (no. of bands)a | No. of no-match isolates (no. of bands)b | |||||
| 777760077760771 | 124326153224 | 4 (9) | 1 (10) | United States | Yes | ||
| 777777607760071 | 214327143228 | 4 (10) | United States | Yes | |||
| 717737777760771 | 223225153322 | 3 (8) | 1 (9) | United States | Yes | ||
| 407777777760771 | 223326153321 | 3 (11, 12, 12) | United States | ||||
| 737776777760601 | 223325153324 | 3 (2) | United States | ||||
| 776177607760771 | 224326133323 | 2 (15) | United States | ||||
| 777777777720771 | 225313153323 | 2 (9, 10) | United States | ||||
| 777776777760771 | 125325143225 | 2 (2) | United States | ||||
| 777776777760601 | 224325153323 | 2 (2, 3) | United States | ||||
| 677737607760771 | 224225163321 | 2 (10) | United States | ||||
| 777777777760771 | 223425153322 | 2 (9) | United States | ||||
| 777777777760771 | 223125153324 | 2 (9, 9) | United States | ||||
| 777777777760731 | 223225153423 | 2 (9, 11) | United States | ||||
| 677777477413771 | 254326223432 | 7 (10-13)e | Philippines | 1.9 | |||
| 777777777760771 | 222315153324 | 2 (9, 10) | Laos | 20.5 | |||
| 000000000000371 | 223325143535 | 2 (15, 16) | Laos | 14.5 | |||
| 703707740003771 | 226425173533 | 2 (13) | India | 0.5 | |||
| 737777777760031 | 223326143321 | 2 (13) | Mexico | 34.5 | Yes | ||
| 000000000003771 | 223325173523 | 2 (13, 14) | China, Korea | 3 | |||
| 703777740003771 | 225425173533 | 2 (10, 13) | India, Nepal | 2 | |||
| 000000000003771 | 223325173533 | 6 (15-22)e | Burma (1), China (2), Laos (2), United States (1) | 4.8f | |||
| 000000000003771 | 223425173533 | 2 (14) | 1 (15) | 1 (12) | Laos (3), United States (1) | 16.3 | Yes |
| 777777774020771 | 225323153323 | 3 (9, 9, 10) | Mexico, Morocco, United States | 3.0 | |||
| 777777777760771 | 223125143324 | 3 (7, 9, 14) | United States (2), Ethiopia | 16 | |||
| 777777774020771 | 225325153323 | 3 (7, 8, 10) | Gambia, Puerto Rico, United States | 12.5 | |||
| 777777777760771 | 222325153324 | 2 (8) | Japan, United States | 43 | |||
Matching IS6110 fingerprints are defined as two patterns that are identical. + 1 band IS6110 fingerprints are defined as a pattern that is an exact match with the exception of having one additional band. Patterns that do not match differ by at least two bands.
The number of copies of IS6110 for each of the isolates is listed in parentheses. If a cluster contained isolates with different IS6110 pattern with the same number of copies of IS6110, then the copy number is repeated.
The number of patients from each country is listed only for those clusters that contain patients from multiple countries.
Length of residency in the United States prior to diagnosis was calculated only for patients born outside of the United States. The average length of residency for clusters containing patients from both the United States and foreign countries does not include the U.S.-born patient.
Only the range of IS6110 copy numbers is listed. The IS6110 fingerprints for these isolates are shown in Figure 1.
Length of residency for the second patient from Laos was unknown. The average was calculated for the remaining four patients.