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. 2017 Jun 22;12(6):e0176596. doi: 10.1371/journal.pone.0176596

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© 2017 McCreight et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 9 — The black line indicates species that have experimental support for the transcription of miR-2355, either in miRBase (human, cow) or from this study (chimpanzee, bonobo, gorilla, and orangutan). The red boxes outline the mature and star sequences within the miRNA. Variants only found among the great apes are highlighted in yellow, while all other variants are marked in grey. Humans have experienced a reversion at position 15 of the mature miRNA, restoring that nucleotide to its ancestral state.