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. 2017 Jun 22;12(6):e0177231. doi: 10.1371/journal.pone.0177231

Table 2. Associations between baseline characteristics and spinal radiographic damage over time.

Total group (n = 80)
B (95% CI) p-value
Male gender 8.87 (3.37–14.38) 0.002
Age (yrs) 0.70 (0.41–0.98) <0.001
 Age 40 years 9.49 (3.53–15.45) 0.002
Symptom duration (yrs) 0.74 (0.36–1.11) <0.001
 Symptom 10 years 12.29 (7.50–17.07) <0.001
Time since diagnosis (yrs) 0.50 (-0.01–1.01) 0.056
HLA-B27+ 0.23 (-7.37–7.82) 0.953
Current smoker 6.16 (-0.05–12.82) 0.070
Smoking duration 0.28 (-0.03–0.58) 0.072
BMI (kg/m2) 1.53 (0.41–2.64) 0.007
 BMI ≥25 kg/m2 12.62 (4.85–20.40) 0.001
NSAID use 4.17 (3.30–11.63) 0.274
DMARD use -2.38 (-9.70–4.95) 0.525
First TNF-α inhibitor -2.70 (-9.65–4.26) 0.447
BASDAI (0–10) -0.59 (-2.17–0.98) 0.461
ASDASCRP 1.91 (-2.30–6.11) 0.375
Patient’s GDA (0–10) -0.33 (-1.59–0.94) 0.610
CRP (mg/L) 0.08 (-0.14–0.30) 0.456
BASFI (0–10) 0.85 (-0.44–2.14) 0.197
mSASSS 1.11 (1.05–1.17) <0.001
≥1 syndesmophyte 18.33 (13.57–23.10) <0.001

See Table 1 for abbreviations.

Etanercept vs. infliximab/adalimumab