. 2017 Jun 22;12(6):e0179429. doi: 10.1371/journal.pone.0179429

Table 3. Descriptive characteristics and levels of moderate-to-vigorous intensity physical activity and sedentary time in children with chronic respiratory diseases.

Reference^*	Place and publication year	Sample group n, male% and age (yrs)	Control group n, male% and age (yrs)	Measurement	Accelerometry methods	MVPA	Sedentary time
Aznar et al [36]	Spain, 2014	n: 47, (51% male)	n: 39; (59% male)	Actigraph GT3X, worn on right hip for 7 days during waking hours	Epoch = 15s, Evenson cut-point [30]	Patients mean 44 (SD 28) min/day	Patients mean 362 (SD 67) min/day
		Age: mean 12.0 (SD 3.0)	Age: mean 12.0 (SD 2.0)		MVPA ≥ 2296 cpm	Control group mean 54 (SD 15) min/day	Control group mean 484 (SD 85) min/day
					Sedentary time < 100 cpm	MVPA significantly lower in patient (p < 0.02)	Sedentary time was lower in patients (p < 0.001)
					Sedentary time < 100 cpm	2% of patients and 34% of control group achieved an average 60 min/ day of MVPA	Sedentary time was lower in patients (p < 0.001)
Kilbride et al [37]	Ireland, 2012	n: 16, (56% male)	n: 99, (48% male)	RT3 worn for 3 days	Epoch and MVPA cut-points not clearly reported	Patients mean boys 15 (SD 3); girls 16 (SD 3) min/day	N/A
		Age: range 10–12	Age: range 10–12		Sedentary time = 0–99cpm	Control group mean boys 23 (SD 6); girls 15 (SD 3) min/day
						MVPA similar in patients and control group
						All patients failed to meet an average of 60 minutes/day MVPA
Smith et al [38]	Germany, 2016	n: 94, (56% male)	n: 590, (40% male)	Actigraph GT3X, worn on right hip for 7 days during waking hours	Epoch = 60s. Freedson cut-point [35]	Patients mean boys 41 (35) 11, 89; girls 43 (36) 14, 71 min/day	N/A
Smith et al [38]	Germany, 2016	Age: mean 15.6 (SD 0.5)	Age: mean 15.7 (SD 0.5)		Epoch = 60s. Freedson cut-point [35]	Control group mean boys 46 (42) 19, 89; girls 38 (34) 13, 70 min/day	N/A
Tsai et al [39]	USA, 2012	n: 27, (70% male)	n: 27, (59% male)	actigraph (Actiwatch 64 MM), worn non-dominant wrist for 7 days during waking hours	Epoch = 60s	Patients mean 265 (SD 83) min/day	Patients mean 87 (SD 48) min/day
		Age: range 9–11	Age: range 9–11		MVPA ≥ 700 cpm	Control group mean 308 (SD 97) min/day	Control group mean 77 (SD 27) min/day
					Sedentary time = 0–49 cpm	MVPA similar in patients and control group (p = 0.09)	Sedentary time difference not significant (p = 0.3)
					Sedentary time = 0–49 cpm	Patients and control group achieved an average of 60 min per day of MVPA	Sedentary time difference not significant (p = 0.3)
Vahlkvist et al [40]	Denmark, 2010	n: 55	n: 154	RT3 worn for 4 weeks during 24 h a day	Epoch and cut-points not clearly reported	Patients mean of 32 (95% CI 5) min/day	Patients mean 1270 (95% CI 15) min/day
		Age: range 6–14	Age: range 6–14			Control group mean 34 (95% CI 3) min/day	Control group mean 1261 (95% CI 9) min/day
						MVPA similar in patients and control group	Sedentary time was similar in patient and control group
						Patients and control group failed to achieve an average of 60 min per day of MVPA	Sedentary time was similar in patient and control group
Van- Gent et al [41]	Netherlands, 2007	n: 81, (58% male)	n: 202, (50% male)	Pam AM 100, worn on hip for 5 days during waking hours	Epoch = 60s	Patients mean 99 (95%, CI 80, 118) min/day	N/A
		Age: mean 9.4 (SD 0.8)	Age: mean 9.4 (SD 0.7)		MVPA cut-points not clearly reported	Control group mean 98 (95%, CI 85, 106) min/day
						MVPA similar in patients and control group
						Patients and control group achieved an average of 60 min per day of MVPA
Yiallouros et al [42]	Cyprus, 2015	n: 36, (64% male)	n: 99, (60% male)	Actigraph worn on wrist for 7 days during waking hours	Epoch not clearly reported	Patients mean 15 (95% CI 10–21) min/day	Patients mean 939 (95% CI 915–963) min/day
		Age: range 8–9	Age: range 8–9		MVPA > 3200 cpm	Control group mean 16 (95% CI 14–19) min/day	Control group mean 927 (95% CI 915–938) min/day
		Age: range 8–9	Age: range 8–9		Sedentary time < 100 cpm	Similar in patients and control group	Similar in patients and control group

cpm: counts per minutes; MVPA: moderate-to-vigorous physical activity; n: Number; S: Second; Data are expressed as mean (SD) unless otherwise in Smith et al [38]: MVPA calculated as mean (Geometric mean) 5^th, 95^th percentile, and Yiallouros et al [42]: MVPA Calculated as geometric means (95% CI) in min/day.; Freedson MVPA cutpoint [35] calculated using the following equation: METS = 2.757 + (0.0015 x counts/min)–(0.08957 x age (yr))–(0.000038 x counts/min x age (yr))

*Studies are recruited healthy control participants and measured MVPA and ST in the same way as in their patient participants and at the same time(referred to here as studies with control group).