. 2017 Jun 22;12(6):e0179429. doi: 10.1371/journal.pone.0179429

Table 5. Descriptive characteristics and levels of moderate-to-vigorous intensity physical activity and sedentary time in children with malignancies.

Reference^*	Place and publication year	Sample group n, male% and age (yrs)	Control group n, male% and age (yrs)	Measurement	Accelerometry methods	MVPA	Sedentary time
Aznar et al [51]	Spain, 2006	n: 7, (57.1% male)	n: 7, (57.1% male	Actigraph MTI, worn on waist for 7 days during waking hours	Epoch = 60s, Freedson cut-point [35]	Patients mean 47 (SD 15) min/day	Patients mean 41 (SD 18) % of time sedentary
		Age: range 4–7	Age: range 4–7		Sedentary time ≤ 100 cpm	Control group mean 72 (SD 25) min/day	Control group mean 42 (SD 11) % of time sedentary
						Significantly lower in patient group than control group (p = 0.04)	Sedentary time was similar in patient and control group (p = 0.07)
						0% of patient, 57% control group achieved an average of 60 min/day of MVPA
Gotte et al [52]	Germany, 2017	n: 28, (57% male)	N/A	Step Watch 3^™ Monitor, worn for 7 days during waking hours	Epoch = 60s	Patients mean 4 (SD 5) min/day	N/A
Gotte et al [52]	Germany, 2017	Age: range 11–15	N/A	Step Watch 3^™ Monitor, worn for 7 days during waking hours	MVPA cut-point not clearly reported	3% (n = 1) of patient achieved an average of 60 min/day of MVPA	N/A
Tan et al [53]	Malaysia, 2012	n: 38	n: 38	Actical, worn on hip for 7 days during all the day	Epoch = 15s	Patients mean 20 (SD 28) min/day	Patients mean 1295 (SD 119) min/day
		Age: range 3–12	Age: range 3–12		MVPA cut off points not reported	Control group mean 168 (SD 56) min/day	Control group mean 925 (SD 111) min/day
		Age: range 3–12	Age: range 3–12		Sedentary time < 100 cpm	Significantly lower in patient group than control group (p < 0.01)	Significantly higher in patients than control group (p < 0.01)

cpm: counts per minutes; MVPA: moderate-to-vigorous physical activity; n: Number; S: Second; Data are expressed as mean (SD) unless otherwise; Freedson MVPA cutpoint [35] calculated using the following equation: METS = 2.757 + (0.0015 x counts/min)–(0.08957 x age (yr))–(0.000038 x counts/min x age (yr))

*2 studies [51, 53] recruited healthy control participants and measured MVPA and ST in the same way as in their patient participants and at the same time (referred to here as studies with control group), 1 study [52] reported patient data in relation to recommendations.