Fig. 7.

The excitatory action of PON on heart. Simultaneous recordings of atrial response to APs in PON. The cardiac compartment of the recording chamber was perfused with 1 mM Cd²⁺. Note a slight adaptation in spikes’ frequency in PON that closely correlates with the inter EPSP intervals. The membrane potential is gradually depolarized after each AP in PON and remained at this new level in-between of period of oscillations. Interestingly, the subsequent burst further depolarized the membrane potential, although not as strong as the preceding one.

Reproduced with permission (Zhuravlev et al., 1997).