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. 2017 Jun 22;12(6):e0179694. doi: 10.1371/journal.pone.0179694

Table 4. Univariate and multivariate analyses for overall survival.

Factor No. of patients Univariate Multivariate
HR (95% CI) p value HR (95% CI) p value
Age
 <80 207 1 1
 ≥80 57 1.44 (0.94–2.14) 0.08 1.34 (0.85–2.06) 0.20
Sex
 Male 174 1
 Female 90 1.12 (0.77–1.59) 0.55
CCI
 0 186 1
 ≥1 78 1.33 (0.92–1.90) 0.12
TNM stage of solid tumor
 II/III 32 1 1
 IV 226 3.29 (1.65–7.80) < 0.005 3.59 (1.80–8.52) < 0.0001
ECOG-PS
 0/1 215 1 1
 2/3/4 48 2.53 (1.64–3.77) < 0.0001 1.58 (0.98–2.49) 0.06
G8 a
 High score 45 1 1
 Intermediate score 115 2.09 (1.17–4.02) < 0.05 1.81 (1.00–3.52) < 0.05
 Low score 104 3.48 (1.97–6.63) < 0.0001 3.34 (1.85–6.47) < 0.0001

Abbreviations: CI, confidential interval; CCI, Charlson comorbidity index; ECOG-PS, Eastern Cooperative Oncology Group performance status.

a: High score, intermediate score, and low score group had a G8 score of 14.5–17, 11–14, and 0–10.5, respectively.