Fig 3. RNA-Seq data for d8 and CLK CPCs confirms enrichment for protein-coding and lncRNA genes associated with CPCs as well as the distribution of differentially-expressed annotated and unannotated genes.

A) RNA-seq-derived RPKM values for pluripotency and cardiac-related genes as proportionally represented by d8/CLK CPCs and undifferentiated ES cells, B) distribution of RPKM values for d8/CLK CPCs and undifferentiated ES cells with respect to known cardiac-related lncRNAs, C) graphical summary of d8/CLK enrichment for panel of lncRNA genes, previously identified by Wamstead et al, in cardiac-differentiated ES cells, D) Biaxial Venn plot showing distribution of differentially-expressed annotated and unannotated genes in d8/CLK CPCs relative to undifferentiated ES cells, highlighting transcripts that are commonly up- and down-regulated.