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. 2017 Jun 22;12(6):e0179947. doi: 10.1371/journal.pone.0179947

Table 4. The relationship of age with left-ventricular (LV) structure/function and aortic function stratified by with and without traditional risk factors and race/ethnicity.

Univariate regression coefficient which represents change in the dependent variable per one-year increase in age. * for p<0.05.

Without risk With risk
White Chinese Black Hispanic White Chinese Black Hispanic
LV Structure (N) 164 64 30 56 1108 315 716 559
 EDV index (ml/m2) -0.355* -0.171 -0.888* -0.25 -0.253* -0.12 -0.23* -0.264*
 ESV index (ml/m2) -0.122* -0.113 -0.215 -0.099 -0.087* -0.045 -0.109* -0.106*
 Mass index (g/m2) 0.02 -0.036 -0.931* -0.088 0.032 0.139 -0.128* -0.035
 M/V ratio (g/ml) 0.006* 0.003 0.000 0.002 0.005* 0.005* 0.002* 0.004*
 SV index (ml/m2) -0.232* -0.058 -0.674* -0.151 -0.166* -0.074 -0.121* -0.157*
 EF (%) 0.000 0.056 -0.165 0.019 -0.002 0.018 0.034 0.017
 Global Ecc (%) 0.044 -0.001 0.062 0.01 0.007 0.019 -0.013 -0.008
LV Myocardium (N) 84 27 13 16 609 121 295 170
 Native T1 (ms) -0.042 -0.855 1.331 -0.222 0.297 0.619 0.77* 0.664*
 Post 12 min T1 (ms) -0.424 -0.007 -2.019 0.481 -0.094 -0.53 -0.258 -0.121
 Post 25 min T1 (ms) -0.976* -0.251 -2.797 0.385 -0.293 -0.234 -0.178 -0.449
 Partition coefficient 0.001 0.000 0.000 0.000 0.001* 0.001 0.001* 0.000
N 43 0 3 3 332 0 150 77
 ECV (%) 0.006 - -0.057 0.176 0.047* - 0.088* 0.066
Aorta (N) 97 56 16 25 654 245 410 234
 PWV (m/sec) 0.109* 0.361* 0.123* 0.187* 0.12* 0.165* 0.156* 0.18*
 AAD (%/mmHg) -0.017 -0.06* -0.013 -0.06* -0.024* -0.027* -0.028* -0.024*
 DAD (%/mmHg) -0.03* -0.07* -0.02 -0.164* -0.015* -0.031* -0.021* 0.004

LV structure index by body surface area. EDV- End-diastolic volume. ESV- End-systolic volume. EF- Ejection fraction. M/V ratio- Mass to end-diastolic volume. SV- Stroke volume. Ecc- Peak regional systolic circumferential strain. ADD- Ascending aortic distensibility. DAD- Descending aortic distensibility. PWV- Pulse wave velocity. ECV- Extracellular volume fraction.