Table 5. Multivariate analysis (adjusted for age, gender, race, and all of the risk factors in the table) of associations of left ventricular (LV) structure/function and aortic function versus risk factors (beta and * for p < 0.05).
EDV index | ESV index | Mass index | SV index | EF | M/V ratio | Native T1 | Post 12min T1 | Post 25min T1 | Partition coefficient | ECV | PWV | AAD | DAD | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hypertension | 1.22* | 0.06 | 5.05* | 1.16* | 0.76* | 0.25* | 0.038 | -2.92 | -2.02 | -0.0019 | 0.13 | 0.2 | -0.1 | -0.2* |
Diabetes | -3.03* | -1.24* | -0.67 | -1.79* | 0.11 | 0.15* | 2.36 | 3.58 | 3.32 | -0.0007 | -0.21 | -0.23 | -0.08 | -0.11 |
BMI ≥30 | -2.69* | -0.94* | 1.19* | -1.76* | -0.36 | 0.15* | 2.84 | -18* | -19.5* | -0.0049 | -0.15 | -0.29 | 0.1 | -0.3* |
Smokers | -0.61 | 0.26 | 0.88* | -0.88* | -0.66* | 0.04 | 2.51 | -1.06 | -2.57 | 0.0047* | 0.36 | 0.41* | -0.00 | 0.05 |
Total cholesterol ≥240mg/dl | 0.2 | -0.18 | 0.54 | 0.37 | 0.6 | 0.12 | 12.52 | -1.76 | -0.64 | 0.0031 | -0.14 | 0.03 | 0.02 | 0.03 |
LDL ≥160 mg/dl | -2.28 | -0.23 | 0.21 | -2.05* | -1.12 | -0.03 | -7.51 | -8.42 | -7.23 | 0.0014 | 0.24 | -0.39 | 0.09 | -0.27 |
Triglycerides ≥150mg/dl | -3.41* | -2.1* | -1.2* | -1.31* | 1.14* | 0.2* | 1.28 | 0.38 | 0.67 | -0.0044 | -0.75* | -0.05 | 0.08 | 0.16 |
Myocardial scar | 5.1* | 5.5* | 7.78* | -0.41 | -4.2* | -0.12 | 8.77* | -13.7* | -10.6* | 0.0177* | -2.53 | -0.29 | -0.21 | 0.25 |
LV structure index by body surface area. EDV- End-diastolic volume. ESV- End-systolic volume. EF- Ejection fraction. M/V ratio- Mass to end-diastolic volume. SV- Stroke volume. ECV- Extracellular volume fraction. PWV- Pulse wave velocity. ADD- Ascending aortic distensibility. DAD- Descending aortic distensibility.