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. 2017 Jun 22;12(6):e0179879. doi: 10.1371/journal.pone.0179879

Fig 6. Inflammatory genes in WAT of mice with inactivated Mest.

Fig 6

A, B, C and D show expression of gene markers for inflammation and macrophage infiltration in WAT of WT and MestpKO (pKO) mice. Gene expression was determined via TaqMan qRT-PCR in total RNA from eWAT and iWAT of wildtype (WT; n = 17), mice with a paternal inactivation of Mest (pKO; n = 10) and subgroups of WT mice with low (LM; n = 6) and high (HM; n = 6) WAT Mest expression after being fed a HFD from 8–16 weeks of age. Gene expression is represented as arbitrary units (AU) normalized to Tbp and presented as the mean ± SEM. Statistical analysis between genotypes within each WAT depot was performed using two-tailed unpaired parametric t-tests and datasets annotated with the same letter indicate no significant differences between groups.