Skip to main content
. 2017 Jun 12;13(6):e1006426. doi: 10.1371/journal.ppat.1006426

Fig 3. Binge-on-chronic alcohol use alters the intestinal microbial and metabolic profile.

Fig 3

(A) Alcohol-treated mice have significantly lower alpha-diversity compared to pair-fed mice as determined by observed species via Qiime. (B) Alcohol-treated mice (red circles) showed significantly different microbial community structures from pair-fed mice (blue circles) as determined by principal coordinate analysis of the weighted UniFrac metric via Qiime. (C) Alcohol-treated mice have altered relative abundance of specific OTUs compared to pair-fed mice. (D) Alcohol-fed (red) mice had significantly different microbial metabolites from pair-fed (blue) mice, as shown by Partial Least Squares Discriminant Analysis. (E) Alcohol-treated mice have altered relative concentration of mirobial metabolites compared to pair-fed mice. *indicates P<0.05, by Mann-Whitney U with both Benjamini-Hochberg and Bonferroni corrections. N = 3-10/group.