Table S3.

Baseline PRO scores of patients who completed 3 years in the study and those who completed ≥1 year but <3 years (non-completers)

PRO score at baseline, mean (SE)	Completers (n=120)	Non-completers (n=213)	P-value (completers vs non-completers)*
SF-12v2 PCS	34.1 (0.92)	34.0 (0.78)	0.2864
SF-12v2 MCS	43.9 (1.19)	42.8 (0.79)	0.2771
MSIS-29 physical	47.8 (1.93)†	47.4 (1.57)†	0.2845
MSIS-29 psychological	40.7 (2.08)†	42.9 (1.53)†	0.2071

Notes:

^*P-value for completers vs non-completers was determined using ANCOVA adjusted for disease level, functional status, number of comorbidities, years since MS diagnosis, and age.

^†n=116 for completers; n=210 for non-completers.

Abbreviations: ANCOVA, analysis of covariance; MCS, Mental Component Summary; MS, multiple sclerosis; MSIS-29, Multiple Sclerosis Impact Scale; PCS, Physical Component Summary; PRO, patient-reported outcome; SE, standard error; SF-12v2, Short Form-12 Version 2.