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. 2017 Jun 22;3:25. doi: 10.1186/s40729-017-0086-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 7 — a–c Histological sections of bone core biopsy taken from the site of implantation using a trephine bur. a Overview image of coronal-apical cut through the entire core biopsy showing formation of new bone (NB) next to old bone of the extraction socket (B). easy-graft CRYSTAL particles (Gr) are embedded in well perfused connective tissue (CT) and new bone (NB) (Azur II and Pararosanilin, original magnification ×50). b Integration of easy-graft CRYSTAL particle (Gr) into newly formed bone (NB) and connective tissue (CT) showing tight contact between graft particle and new bone. c High magnification (×200) images of the interface between graft particle (Gr) and new bone (NB) showing osteoblasts (OB) forming osteoid (O) and formation of new bone (NB) on the surface of easy-graft CRYSTAL particles (Gr) (Azur II and Pararosanilin, original magnification ×200)