Table 2.

Changes in functional connectivity differ for relaxing and stimulating acupressure treatments.

Region	MNI coordinates (x y z)			Z-score	Cluster size (voxels)	p-Value
Posterior insula seed-based functional connectivity
Stimulating > relaxing
L DLPFC	−37	45	21	4.62	498	0.001 FWE
Relaxing > stimulating
N.S.
Default mode network functional connectivity with independent component analysis
Stimulating > relaxing
L pulvinar thalamus	−19	−31	15	4.32	161	0.035 FWE
R pulvinar thalamus	13	−33	13	4.07	148	0.048 FWE
Relaxing > stimulating
SC/PAG	−3	−31	−3	3.95	22	0.003 FWE*

Significant connectivity relationships are in italics.

DLPFC, dorsolateral prefrontal cortex; SC/PAG, superior colliculus/periaqueductal gray; L, left; R, right; FWE, family-wise error; N.S., not significant; MNI, Montreal Neurological Institute.

*Significant at p < 0.05 with small volume correction.