Table 3.

Correlation between MDAS score and the levels of miRs or ratios.

Highest MDAS score	Unadjusted		Adjusted by age, sex, and total RNA concentration
	Regression coefficient ± SE	P-value	Regression coefficient ± SE	P-value
miR-146a in CSF	0.852 ± 1.087	<0.001∗∗∗	0.872 ± 1.101	<0.001∗∗∗
miR-146a in serum	-0.400 ± 2.659	0.011∗∗	-0.403 ± 2.750	0.026∗
miR-146a CSF/serum ratio	0.817 ± 0.643	<0.001∗∗∗	0.817 ± 0.652	<0.001∗∗∗
miR-181c in CSF	0.680 ± 0.698	<0.001∗∗∗	0.682 ± 0.720	<0.001∗∗∗
miR-181c CSF/serum ratio	0.307 ± 0.424	0.054	0.302 ± 0.439	0.078

The left panel of the table illustrates the results of the regression coefficients for miR-146a in CSF, miR-146a in serum, miR-146a CSF/serum ratio, miR-181c in CSF and miR-181c CSF/serum ratio with the highest MDAS score in a simple linear regression. The right panel of the table shows the regression coefficients in multiple linear regressions, including adjustment for confounding factors. MDAS, Memorial Delirium Assessment Scale; CSF, cerebrospinal fluid; SE, standard error, ^∗P < 0.05; ^∗∗P < 0.01; ^∗∗∗P < 0.001.