Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 22;7:4071. doi: 10.1038/s41598-017-03199-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Ability of single parameter conformational ensembles to predict TFBS in PIQ data. (a) TFBS’s were classified from genomic control positions using 65 ensemble features at motif site and its +/−200-nt distance using 7-nt window at each position in each of the 1312 TFs and distribution of AUC for all such predictions was represented in a boxplot. (b) The data were separated for motif positions (0 to 15 bases from motif start) and (c) outside of it. Results in (a–c) indicated that “opening” ensemble is the best predictor of TFBS in both regions (even if the difference between AUC is small), followed by parameters whose static values are also used in DNAshape (see (d)) (d) Relative number of times a conformational parameter appeared in the top-ranked position in all positions in all TFs was counted.