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. 2017 Jun 22;7:4071. doi: 10.1038/s41598-017-03199-6

Table 2.

Transcription factors, which show significantly better (>5% AUC) binding site predictability using (a) DynaSeq than DNAshape features and (b) vice versa of (a).

S. No. TF ID TF Name AUC gain (%) S. No. TF ID TF Name AUC gain (%)
(a)
1 MA03841 SNT2 10.0 47 MA01931 Lag1 5.8
2 CN00091 LM9 9.7 48 PB00051 Bbx1 5.7
3 PB00801 Tbp1 9.4 49 PB01791 Sp1002 5.7
4 MA03511 DOT6 9.3 50 MA02591 HIF1AARNT 5.6
5 PL00131 hlh2hlh15 8.6 51 MA02671 ACE2 5.6
6 PH00341 Gbx2 8.6 52 CN00841 LM84 5.6
7 CN00441 LM44 8.2 53 MA03501 TOD6 5.6
8 PH01681 Hnf1b 8.2 54 PB01261 Gata52 5.6
9 PH01641 Six4 8.0 55 PF00101 GCCATNTTG 5.6
10 MA04001 SUT2 7.7 56 PB01321 Hbp12 5.6
11 PB01651 Sox112 7.7 57 PF00561 GGGTGGRR 5.6
12 MA03351 MET4 7.5 58 MA02371 pan 5.5
13 MA01382 REST 7.4 59 MA01421 Pou5f1 5.5
14 MA01551 INSM1 7.3 60 POL0121 TATABox 5.5
15 MA02251 ftz 7.1 61 PB01111 Bhlhb22 5.5
16 MA00831 SRF 7.1 62 MA02321 lbl 5.5
17 CN00271 LM27 7.0 63 MA00411 Foxd3 5.5
18 MA01431 Sox2 7.0 64 PB01631 Six62 5.4
19 PH01071 Msx2 7.0 65 MA04071 THI2 5.4
20 MA00071 Ar 7.0 66 PF01401 RNGTGGGC 5.4
21 PB01981 Zfp1282 6.9 67 PB01751 Sox42 5.4
22 MA03861 TBP 6.9 68 CN02111 LM211 5.4
23 PH01171 Nkx31 6.8 69 CN00521 LM52 5.4
24 PF00231 TAATTA 6.7 70 PB01001 Zfp7401 5.4
25 PL00041 hlh27 6.7 71 MA02861 CST6 5.4
26 PB01571 Rara2 6.7 72 MA01851 Deaf1 5.3
27 PH01701 Tgif2 6.6 73 MA02701 AFT2 5.3
28 PH01161 Nkx29 6.5 74 PF00761 CAGGTA 5.3
29 PL00181 hlh25 6.4 75 MA03141 HAP3 5.3
30 MA01031 ZEB1 6.4 76 PH01731 Uncx 5.2
31 PH01481 Pou3f3 6.3 77 PF00121 CAGGTG 5.2
32 MA00661 PPARG 6.2 78 CN01571 LM157 5.2
33 CN02301 LM230 6.2 79 PF01421 ACAWYAAAG 5.2
34 MA00181 CREB1 6.2 80 MF00031 RELclass 5.2
35 PF01131 AACYN NNNTTCCS 6.2 81 PH00981 Lhx8 5.2
36 MA00601 NFYA 6.1 82 PF00131 CTTTGT 5.2
37 PB01491 Myb2 6.1 83 PH00971 Lhx62 5.2
38 PH01221 Obox2 6.0 84 PB01501 Mybl12 5.2
39 PH01621 Six2 6.0 85 PH01091 Nkx11 5.2
40 CN00821 LM82 6.0 86 PB00081 E2F21 5.2
41 MA01591 RXRRARDR5 6.0 87 CN00591 LM59 5.1
42 PH00701 Hoxc5 5.9 88 MA02581 ESR2 5.1
43 CN01191 LM119 5.9 89 CN02101 LM210 5.1
44 MA04111 UPC2 5.9 90 MA01101 ATHB5 5.0
45 MA00861 sna 5.8 91 MA00792 SP1 5.0
46 PF01631 GGAR NTKYCCA 5.8
(b)
S. No. TF ID TF Name AUC gain (%)
1 MF00071 bHLHzipclass 8.0
2 MA02771 AZF1 7.0
3 PH00011 Alx3 7.0
4 MA01951 Lim3 6.5
5 PB01861 Tcf32 6.2
6 PF01191 GGGNRMNNYCAT 5.7
7 MA01891 E5 5.6
8 PH00111 Alx12 5.5
9 CN00361 LM36 5.4
10 MA01621 Egr1 5.3
11 MA00131 brZ4 5.3
12 PB01851 Tcf12 5.2