Table 5.
Changes in immunohistochemical scoring according to histopathological and clinical characteristics of endometrial cancer patients.
| Protein | Tumor/control | Tumor differentiation (high grade vs. low grade) | Menopausal status | FIGO stage (IA vs. IB-IV) | Myometrial invasion (yes/no) | Lympho-vascular invasion (yes/no) | Vital status | |
|---|---|---|---|---|---|---|---|---|
| Fold-change | p | p | p | p | p | p | p | |
| STS | 0.73 | 0.0219 | 0.6383 | 0.8962 | 0.8787 | 0.5752 | 0.693 | 0.7503 |
| HSD17B2 | 1.45 | 0.0236 | 0.5055 | 0.5419 | 0.9576 | 0.45 | 0.7844 | 0.4178 |
| SULT1E1 | 0.59 | 0.0678 | 0.657 | 0.0535 | 0.8447 | 0.6497 | 0.1287 | 0.3016 |
The differences in expression levels in tumor as compared to the adjacent control endometrium were analyzed using Wilcoxon matched-pair tests. Stratification analysis were done using 2-way ANOVA. The differences in p-values of < 0.05 were considered significant and are marked in bold.