Table 7.
Control | Hyperoxia | |
Bcl-2 (n = 5) | 100 | 96 ± 8 |
Bax (n = 5) | 100 | 134 ± 28* |
Cytochrome c (n = 5) | 100 | 102 ± 15 |
Mitochondrial membrane potential | 100 | 81 ± 8* |
Early apoptotic TIIcells | 100 | 101 ± 26 |
Late apoptotic TIIcells | 100 | 94 ± 22 |
Cell death detection ELISA | 100 | 104 ± 13 |
Several apoptotic parameters were determined in freshly prepared TIIcells of rats exposed to air (control) or oxygen for 48 hrs (hyperoxia) as described in Materials and Methods. Values are means ± S.D. given in arbitrary units (control = 100) of n = 3 independent experiments unless stated otherwise. Asterisk indicates a significant difference to control (p < 0.05).