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Effect of Cl- conductance inhibitors on TEP. In the absence of luminal Cl- (Gluconate substitution), two new inhibitors GlyH-101 (50 μM) and CFTRInh-172 (5 μM, re: A. Verkman) showed at least partial inhibition of the Cl-:Gluconate anion diffusion potential. NPPB (100 μM) seemed to be the most effective inhibitor in terms of depolarizing the TEP.
