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. 2017 Jun 22;7:4064. doi: 10.1038/s41598-017-03970-9

Table 2.

Pharmacokinetic parameters of cyadox in plasma and ileum fluid (mean ± SD, n = 6).

Variables (units) Plasma Ileum fluid
Cmax (μg/mL) 0.03 ± 0.03 23.66 ± 0.92
Tmax (h) 2.41 ± 1.32 1.96 ± 0.03
T1/2 λz (h) 3.61 ± 1.87 5.86 ± 0.71
AUC0–last (μg ∙ h/mL) 0.22 ± 0.16 106.40 ± 12.68
AUC0–∞ (μg ∙ h/mL) 0.26 ± 0.21 112.35 ± 14.07
AUMC0–last (μg ∙ h2/mL) 1.14 ± 0.42 568.49 ± 110.27
AUMC0–∞(μg ∙ h2/mL) 1.86 ± 0.92 743.23 ± 165.71
MRT0–last (h) 5.19 ± 3.21 5.34 ± 0.39

Notes: The pharmacokinetic parameters were calculated by non-compartment model.