Table 4.

PK-PD modeling of ex vivo cyadox after oral administration at a dose of 30 mg/kg.

Parameters	Units	Values
Emax	Log CFU/mL	2.71 ± 0.37
E0	Log CFU/mL	−4.61 ± 0.69
Emax−E0	Log CFU/mL	7.32 ± 1.06
EC50	h	30.07 ± 6.94
N (slope)	/	4.62 ± 0.72
AUC24h/MIC for bacteriostatic effect	h	26.72 ± 6.28
AUC24h/MIC for bactericidal effect	h	39.54 ± 7.31
AUC24h/MIC for eradication effect	h	50.69 ± 9.16