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. 2017 Jun 22;7:4041. doi: 10.1038/s41598-017-04151-4

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Changes in texture feature distributions with different imaging and pre-processing settings. The box plots show the distribution of contrast, correlation, energy, entropy and homogeneity for the 72 ROIs in the glioma data set. The box shows the first and third quartiles, with the median value indicated by the center line. The whiskers show the extreme values. An asterisk in the upper left corner indicates that at least one pair of settings is significantly different.