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. 2017 Jun 22;7:4041. doi: 10.1038/s41598-017-04151-4

Table 1.

Percentage change in texture features when expanding the ROI by one voxel.

AutoROI (%) Manual (%) Manual/AutoROI
Autocorrelation −40.8 4.59 0.112
Cluster Prominence −53.9 111 2.05
Cluster shade −8840 286 −0.0323
Contrast −43.9 26.1 −0.595
Correlation −5.91 −5.31 0.898
Difference entropy −9.69 3.45 −0.356
Difference variance −38.5 35.8 −0.930
Dissimilarity −0.276 0.0886 −0.321
Energy 57.8 30.3 0.525
Entropy −6.32 1.50 −0.237
Homogeneity 38.8 3.53 0.0910
Information measure of correlation 1 −25.8 −11.3 0.437
Information measure of correlation 2 −10.1 −2.95 0.293
Inverse difference 25.1 1.13 0.0449
Maximum probability 0.422 25.5 60.5
Sum average, μ x+y −22.5 −4.19 0.186
Sum entropy −8.18 0.386 −0.0472
Sum of squares −48.2 17.6 −0.366
Sum variance −49.3 15.4 −0.312

The sensitivity of AutoROI and a manual level of 500 and 1500 mm2/s to the definition of the ROI for a patient with a tumor close to the left lateral ventricle, in the slice shown in Fig. 3.