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. Author manuscript; available in PMC: 2018 Jun 1.
Published in final edited form as: Environ Microbiol. 2017 Mar 21;19(6):2182–2191. doi: 10.1111/1462-2920.13700

Fig. 4.

Fig. 4

(A) NapB1-3 share a high level of amino acid sequence identity with fur1-3 from the furaquinocin pathway in Streptomyces sp. KO-3988, which is responsible for the biosynthesis of 8-amino-flaviolin. (B) Nap pathway in Streptomyces sp. CNQ-525 (modified from Winter et al., 2007). This pathway favors the biosynthesis of compounds in the napyradiomycin class in oxic conditions. The production of 8-amino-flaviolin is favored in hypoxic conditions in strain CNQ-525. (C) Representative structure of napyradiomycin, with moiety originating from 8-amino-flaviolin highlighted in blue.