Table 1.
T2 SCI (n = 8) | CON (n = 6) | |
---|---|---|
Anatomical data | ||
Body mass (g) | 259.13 ± 14.49 | 272.17 ± 7.86 |
Heart mass (g) | 1.013 ± 0.18† | 1.08 ± 0.11 |
Heart mass/femur | 1.22 ± 0.22 | 1.42 ± 0.27 |
Collagen content | 0.0095 ± 0.0013†† | 0.0016 ± 0.0003 |
Echocardiographic data | ||
Dimensions | ||
LVIDd (mm) | 6.95 ± 0.49††† | 7.67 ± 0.56 |
LVIDs (mm) | 4.44 ± 0.30†† | 3.92 ± 0.26 |
EDV (µl) | 253.03 ± 40.0††† | 315.9 ± 52.57 |
ESV (µl) | 90.13 ± 14.45†† | 67.42 ± 10.47 |
Systolic function | ||
SV (µl) | 162.89 ± 41.27††† | 248.48 ± 46.44 |
EF (%) | 63.64 ± 7.34† | 78.49 ± 2.68 |
CO (ml/min) | 44.56 ± 10.73† | 76.25 ± 10.06 |
Diastolic function | ||
E (cm s−1) | 63.19 ±8.621††† | 81.23 ± 16.82 |
A (cm s−1) | 46.011 ± 9.42 | 36.58 ± 23.7 |
E/A | 1.4 ± 0.17† | 2.22 ± 0.71 |
LVIDd, left ventricular internal diameter at end-diastole; LVIDs, left ventricular internal diameter at end-systole; EDV, end-diastolic volume; ESV, end-systolic volume; SV, stroke volume; EF, ejection fraction; CȮ, cardiac output; E, peak transmitral filling velocity during early diastole; A, peak transmitral filling velocity during late diastole; CON, uninjured control; SCI, spinal cord injury; Data are displayed as mean ± SD
P < 0.001 vs. CON;
P < 0.01 vs. CON;
P < 0.05 vs. CON.