Skip to main content
. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Exp Gerontol. 2016 Dec 22;109:99–107. doi: 10.1016/j.exger.2016.12.016

Table 2.

Splenic leukocyte characteristics

Group YNC ONC OCR OVR
Spleen mass (g) 0.097 ± 0.001 0.124 ± 0.042 0.045 ± 0.002† 0.112 ± 0.024
Total number of CD45+ cells (x107) 4.1 ± 0.6 7.4 ± 1.2 4.2 ± 0.7 4.9 ± 0.5
% CD3+ cells 18.5 ± 1.0 14.1 ± 1.7 16.2 ± 2.5 17.1 ± 2.5
CD4/CD8 ratio 1.23 ± 0.06 1.00 ± 0.13 1.05 ± 0.29 1.04 ± 0.26
% CD19+ cells 60.8 ± 0.8 63.6 ± 5.4 61.9 ± 2.8 67.2 ± 3.5
% CD11b+ cells 7.3 ± 1.2 10.3 ± 1.2 13.4 ± 1.0* 9.5 ± 1.3

YNC: young normal chow, ONC: old normal chow, OCR: old caloric restricted, OVR: old voluntary running. n = 5–11/group. Differences were assessed with one way ANOVA and LSD post hoc tests.

*

Different from YNC, p < 0.05

Data are means ± SEM.