Figure 3.

Location of the LdtR binding sequence in the promoter region of L. asiaticus genes. The location of the LdtR binding site was predicted for every homologue in L. asiaticus of the differentially expressed genes in L. crescens using RegPredict (Pagliai et al., 2014). The genes were clustered using K‐means (Hartigan and Wong, 1979). The fold change of the transcript levels of the RNA‐seq experiments in L. crescens and the location of the predicted LdtR binding site in L. asiaticus are shown. In grey circles, genes up‐regulated under phloretin treatment with a centre at the position −52. In black squares, genes down‐regulated under phloretin treatment with a centre at the position −190. Empty symbols represent the genes whose predicted binding site was not clustered between the two main groups. The location of the binding site is relative to the translational start site (indicated with an arrow at the position 1).