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. 2017 Apr 18;10(4):873–885. doi: 10.1111/1751-7915.12716

Figure 5.

Figure 5

UPLC analysis of Streptomyces sp. NTK937 wild‐type (WT) and different mutant strains. (A) AMP‐dependent synthetase‐ligase‐deficient mutant strains. (B) 2,3‐dihydro‐2,3‐dihydroxybenzoate dehydrogenase‐deficient mutant strains. (C) Isochorismatase‐deficient mutant strains. (D) Anthranilate synthase‐deficient mutant strains. Extracts were obtained from cultures grown in R5A medium for 7 days. UPLC chromatograms were analysed at 330 nm. Labelled peaks correspond to caboxamycin A (1), O‐methylcaboxamycin (2) and 3′‐hydroxycaboxamycin (3).