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. 2017 May 1;292(25):10639–10650. doi: 10.1074/jbc.M117.787606

Table 1.

Kinetic parameters for wild type and variants of BT3312

Substrate kcat/Kma Relative activity
Enzyme variant
    Wild type 1,6-β-Glucan (pustulan) 1776 ± 20.6 1
    Wild type 1,3-β-Glucan 0 0
    Wild type 1,4-β-Glucan 0 0
    Wild type 1,6-β-Galactan 0 0
    E238A 1,6-β-Glucan (pustulan) 0 0
    H281A 1,6-β-Glucan (pustulan) 10 ± 1 0.006
    N282A 1,6-β-Glucan (pustulan) 17 ± 1 0.009
    D286A 1,6-β-Glucan (pustulan) 475 ± 30 0.27
    E339A 1,6-β-Glucan (pustulan) 0 0
    E339Q 1,6-β-Glucan (pustulan) 0 0
    W345A 1,6-β-Glucan (pustulan) 7 ± 1 0.004
    C393S 1,6-β-Glucan (pustulan) 9 ± 1 0.005
    C396S 1,6-β-Glucan (pustulan) 55 ± 3 0.03

Oligosaccharides
    Wild type 1,6-β-Glucotriose 1.7 × 106 ± 1.1 × 104
    Wild type 1,6-β-Glucotetraose 2.6 × 106 ± 3.4 × 105
    Wild type 1,6-β-Glucohexaose 6.0 × 106 ± 6.0 × 105
    Wild type 1,6-β-Glucooctaose 6.4 × 106 ± 1.4 × 105

a The kinetic parameter is mg ml−1 min−1 for pustulan and m−1 min−1 for glucooligosaccharides.