Table 4.
Estimated Genetic and Phenotypic Correlations between Metabolic Syndrome Severity Score and Individual Components
Cohort | SBP | WC | LnTG | HDL | FG |
---|---|---|---|---|---|
Genetic
| |||||
JHS | 0.39 (0.17) | 0.87 (0.04) | 0.71 (0.06) | −0.56 (0.07) | 0.90 (0.05) |
PLRS-Blacks | 0.27 (0.38) ns | 0.83 (0.12) ns | 0.47 (0.25) ns | −0.69 (0.24) ns | 1.0 ns |
PLRS-Whites | 0.67 (0.16) | 0.77 (0.08) | 0.90 (0.05) | −0.71 (0.10) | 0.61 (0.13) |
TOPS | 0.56 (0.10) | 0.74 (0.06) | 0.71 (0.06) | −0.51 (0.10) | 0.49 (0.10) |
| |||||
Phenotypic*
| |||||
JHS | 0.15 | 0.77 | 0.54 | −0.43 | 0.80 |
PLRS-Blacks | 0.53 | 0.82 | 0.46 | −0.50 | 0.65 |
PLRS-Whites | 0.47 | 0.74 | 0.82 | −0.67 | 0.51 |
TOPS | 0.43 | 0.74 | 0.68 | −0.45 | 0.55 |
All correlations significant (p<0.05) unless otherwise noted;
not significant (p > 0.05)
Phenotypic correlations are estimated in SOLAR without SE, so SE is not presented; All correlation coefficients were significant (P < 0.01).
SBP: Systolic Blood Pressure; WC: Waist Circumference; LnTG: natural logarithm of Triglycerides, HDL: High Density Lipoprotein; FG: Fasting Glucose; JHS: Jackson Heart Study; PLRS: Princeton Lipid Research Study; TOPS: Take Off Pounds Sensibly