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. 2017 Jun 15;8:15337. doi: 10.1038/ncomms15337

Figure 10. Regulation of anthracycline toxicity and ALDH2 expression by VHL are conserved.

Figure 10

(a)The mRNA of vhl-1 in vhl-1 RNAi C.elegans. (b) The mortality of indicated vhl-1 RNAi C.elegans treated by 20 μg ml−1 doxorubicin for different time. (c) The mRNA of alh-1 in alh-1 RNAi C.elegans. (d) The mortality of indicated alh-1 RNAi C.elegans treated by 20 μg ml−1 doxorubicin for different time. (e) The mRNA of alh-1 detected by semi-quantitative RT–PCR in vhl-1 RNAi C.elegans. (f) The mRNA expression of indicated genes detected by semi-quantitative RT–PCR in vhl-1 deficiency C.elegans CB5602. Ctrl represents control. RNAi represents RNA interference. Twenty-five cycles used for semi-quantitative RT–PCR. Columns, means of three independent experiments; bars, s.d. (*P<0.05, **P<0.01 for t-test).