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. 2017 Jun 15;8:15337. doi: 10.1038/ncomms15337

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Copyright © 2017, The Author(s)

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(a) Representative immunohistochemistry images of ccRCC samples for the low and high expressions of indicated proteins. The scale bar represents 100 μm. (b) VHL, HNF-4α and ALDH2 expression scores are shown as box plots, with the horizontal lines representing the median; the bottom and top of the boxes representing the 25th and 75th percentiles, respectively; and the vertical bars representing the range of data. We compared renal clear cell carcinoma tissues with matched adjacent tissues (n=114). Any outliers are marked with a circle. P value is calculated via t-test. (c) Correlation analysis of VHL, HNF-4α and ALDH2 expression are calculated via Pearson’s χ² test and all the P value are less than 0.01.