Table 4.

Odds ratios for risk of worsening or improvement in EQ-5D anxiety/depression dimension when pain/discomfort dimension worsens or improves, respectively (not by treatment)

	Odds ratio (95% CI)
	Week 13 (n = 1403)	Week 25 (n = 1087)	Week 37 (n = 914)	Week 49 (n = 770)	Week 61 (n = 625)
Worsening of Anxiety/Depression with worsening Pain/Discomfort	2.495 (1.749–3.559)	3.623 (2.426–5.410)	2.259 (1.431–3.564)	2.696 (1.690–4.303)	1.457 (0.832–2.554)
Improvement in Anxiety/Depression with improvement in Pain/Discomfort	2.514 (1.591–3.972)	1.890 (1.159–3.083)	2.937 (1.738–4.964)	2.916 (1.643–5.177)	2.789 (1.380–5.638)

CI confidence interval