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. 2017 Jun 23;8:30. doi: 10.1186/s13229-017-0148-6

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — c-Fos staining in Fmr1 mice. The intensity of c-Fos staining (a–c) and the number of c-Fos-positive cells (d–f) in the lateral amygdala (a, d), medial amygdala (b, e), and prelimbic cortex (c, f). Insets show anatomical regions assessed shaded in gray. Representative staining for c-Fos in the PLC of (g) wildtype mouse exposed to a non-social stimulus, (h) wildtype mouse exposed to a social stimulus, (l) Fmr1 KO mouse exposed to a non-social stimulus, and (j) Fmr1 KO mouse exposed to a social stimulus. The number of c-Fos-positive cells was compared between brain regions for each subject. There was a significant positive correlation between LA and MA, and a significant negative correlation between each amygdalar region and the PLC (k)