Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jun 21;37(25):6007–6020. doi: 10.1523/JNEUROSCI.0772-16.2017

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Sullivan et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Figure 4. — Basal, but not capsaicin-induced, mEPSCs are reduced in lamina II neurons from stg/stg mice. A, Representative recording of mEPSCs from a lamina II neuron of a wt mouse showing the effect of bath-applied capsaicin (0.1 μm). Inset (bottom), Changes in mEPSC frequency (20 s bins). B, Same as A, but for a neuron from an stg/stg mouse. C, Average mEPSC waveforms from the recording in A, together with cumulative probability plots for the amplitudes of control and capsaicin-induced mEPSCs. D, Same as C, but for the neuron in B. E, Summary data for mEPSC amplitudes. A two-way “split plot” ANOVA indicated no significant main effect of genotype (F_(1,26) = 2.96, p = 0.098), a significant main effect of capsaicin treatment (F_(1,26) = 14.73, p = 0.00071), and a significant interaction between genotype and capsaicin treatment (F_(1,26) = 13.88, p = 0.00095). F, Summary data for capsaicin-induced mEPSCs showing the weighted mean single-channel conductance from psNSFA. Box-and-whisker plots as in Figure 2. ***p < 0.001.