. 2017 Jun;18(6):501–511. doi: 10.1631/jzus.B1500291

Table 3.

Assessments of degeneration, necrotic changes graded as none, mild, moderate, severe, and extremely severe by light microscopy of kidney sections at 40× magnification in 10 randomly selected areas

Group	Degeneration	Necrosis	Inflammatory cell	Biliary hiperplasia
Liver
I	0.00±0.00^b	0.00±0.00^b	0.00±0.00^c	0.00±0.00^c
II	0.83±0.31^b	0.00±0.00^b	0.00±0.00^c	0.00±0.00^c
III	2.33±0.21^c	1.17±0.31^c	1.17±0.31^c	1.50±0.43^b
IV	3.67±0.21^a	2.50±0.22^a	2.50±0.22^a	2.67±0.21^a
V	1.83±0.17^bc	0.83±0.17^bc	0.33±0.21^b	1.17±0.31^b
VI	3.00±0.26^ab	1.83±0.17^ab	1.83±0.17^ab	1.83±0.31^ab

P	^***	^***	^***	^***

Kidney
I	0.00±0.00^c	0.00±0.00^c	0.00±0.00^c
II	0.50±0.22^c	0.00±0.00^c	0.00±0.00^c
III	2.50±0.22^b	1.00±0.37^b	0.83±0.31^bc
IV	4.00±0.00^a	3.17±0.17^a	2.00±0.26^a
V	2.00±0.00^b	1.17±0.17^b	0.50±0.22^c
VI	3.33±0.21^a	2.33±0.21^a	1.67±0.21^ab

P	^***	^***	^***

Group I: control group; Group II: HPE1-administered group; Group III: HPE2-administered group; Group IV: gentamicin-administered group; Group V: gentamicin-plus-HPE1-treated group; Group VI: gentamicin-plus-HPE2-treated group. Data are expressed as mean±SEM (n=6). Values with different superscripts within one column differ significantly.

^***

P<0.001