GPX immunohistochemistry in the hippocampal CA1 region of the (A) vehicle-sham-, (B) CIL-sham-, (C and E) vehicle-ischemia- and (D and F) CIL-ischemia-groups following ischemia-reperfusion. GPX immunoreactivity is detected well in the SP of the vehicle-sham-group; the immunoreactivity is significantly increased in the CIL-sham-group. In the vehicle-ischemia-group, GPX immunoreactivity is hardly observed in the SP at 5 days post-ischemia; however, in the CIL-ischemia-group, GPX immunoreactivity is significantly higher than that in the vehicle-ischemia-group. Scale bar, 100 µm. (G) ROD as % values of GPX immunoreactivity in the SP of each group (*P<0.05 vs. vehicle-sham-group; #P<0.05 vs. corresponding vehicle-ischemia-group; †P<0.05 vs. respective pre-time point group). The bars indicate the means ± standard error of mean. GPX, glutathione peroxidase; CIL, Chrysanthemum indicum Linné extract; ROD, relative optical density; SO, stratum oriens; SP, stratum pyramidale; SR, stratum radiatum.