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. 2017 May 31;16(1):499–506. doi: 10.3892/mmr.2017.6660

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 2. — Immunohistochemical staining for SOX7 in pancreatic cancer and adjacent non-cancerous pancreatic tissues in a TMA. (A) Immunohistochemistry staining for SOX7 in the pancreatic cancer TMA cohort. (B) IRS of SOX7 in pancreatic cancer were lower than those observed in the adjacent normal pancreatic tissues IRS: **P=0.005, pancreatic cancer (2.39±1.88) vs. benign (4.80±0.45). Data were presented as the mean ± standard deviation. **P<0.01. The immunohistochemistry staining indicated that SOX7 immunostaining primarily occurred in the cytoplasm and cellular membrane of pancreatic cancer tissue cells. The intensities of SOX7 immunostaining observed were (C) intermediate and (D) weak, with no strong staining observed in cancer tissues. Left image, magnification ×100 and right image, magnification ×400; the red squares indicate the area shown at higher magnification. (E) Intermediately immunohistochemistry staining in adjacent non-cancerous pancreatic tissue cells. SOX7, sex determining region Y-box 7; TMA, tissue microarrays; IRS, immunoreactivity scores.